Just like there are Olympic Games for world’s greatest athletes, for computational biologists, there is CASP (Critical Assessment of Structure Prediction). We just had the 13th competition (it takes place biannually). Until recently, it was just academic groups that played this game but now Tencent and Microsoft also show up. Like CASP12 in 2018, DeepMind’s AlphaFold came top but that is not the big news. The big news this time is by how much.

The full paper is not yet published but AlphaFold’s 2020 performance is the biggest advance in CASP ever. Last year the average performance of AlphaFold was…

The Company Your Proteins Keep May Kill You or Make You Live Longer

This week, Draper Esprit has announced that it is leading a significant investment round ($31m) into Cambridge (UK) based Fluidic Analytics to help it scale fast. BGF and Delin Ventures have joined our syndicate; existing investors IQ Capital and Amadeus have joined the round. Strategically, Fluidic Analytics fits within Draper Esprit’s deep tech/healthtech investing focus. Just like Graphcore and Evonetix, Fluidic Analytics is using deep technical knowledge and strong intellectual property (17 families of granted and applied patents) to attack a very large global problem.

Here Is…

The genomic century has only just started. Get your seatbelts on!

Today, we are delighted to announce that Draper Esprit and DCVC are leading a $12.3m investment in Cambridge UK based company, Evonetix . I will be joining the board along with Matt Ocko, co founder of DCVC, and a leading voice in Silicon Valley deep tech VC community.

Evonetix is making a DNA chip to accurately synthesise long pieces of DNA and fits with Draper Estprit’s investment thesis to back the most promising companies downstream of DNA sequencing (previously, we invested in Horizon Discovery which does CRiSPR gene editing and Fluidic Analytics which does protein characterisation — both also based…

Ieso’s aim is to improve access and quality of CBT for millions of people and we are delighted to be a part of their journey

Video Announcing Draper Esprit’s Investment into Ieso

Imagine a health debate where ministers promised that at least 15% of cancer sufferers will receive evidence based proven medical treatments. Or that they were hoping that at least 25% of expectant mothers will get access to safe childbirth. You would rightly think that we are talking about a very poor level of healthcare access. But if you apply this to access to psychological therapies by people suffering from common mental health conditions, this is where many developed economies are today, in 2017!

Cost of mental health conditions is estimated to be~£100b in…

For those of you who have not experienced the frictionless new world of telemedicine, you may be excused for not believing this headline.

Your disbelief is supported by data. According to the King’s Fund, the number of GP appointments went up by 13% this year; increasingly, people are finding it harder to see their GP at their time of choice. A survey by Pulse (a publication for doctors) found that the average waiting time for a routine appointment is two weeks(!) This is not limited to the UK. Across the pond, in a very different healthcare system, there is a very similar picture emerging.

There are two key factors which explain why this is happening. The first is a simple demand and supply…

One day, today’s best healthcare will look stupid. Very stupid.

Today, I am excited. The sun is out but more importantly, the news is out! Draper Esprit successfully raised another £100m in its listed fund Draper Esprit (LN:GROW). This, along with cash from recent exits EIS fund, Secondaries and VCT partnership gives Draper Esprit over £160m of cash to invest over next couple of years.

If you think in terms of a typical five- year fund, this is the equivalent of a £800 million ($1 billion) fund.

Sorry, I don’t mean to bore you with numbers. The reason for this post is to re emphasise our commitment to digital health…

Data Science has been a Force Behind Medical Progress

Over 250 years years ago Edward Jenner, the “father of immunology” was born in Berkeley (Gloucestershire, not California). He spent years studying small pox, one of the greatest killers of the period. Over many years he made a crucial observation: those who were infected with a certain strain of cowpox (a less severe and non life threatening virus) were very unlikely to get small pox. He tested his intervention and published An Inquiry Into the Cause and Effects of the Variolae Vaccinae. The study was based on his study of twenty-three cases.

A picture of page 36 of An Inquiry Into the Cause and Effects of the Variolae Vaccinae (1798) by Edward Jenner describing the case of John Baker (Case 18 of 23)

This is an early example of data aggregation…

It must be a slow news day at the BBC but this is an important wake-up call for healthcare service providers. A Belfast man who was not well (I am guessing he had man-flu) ordered chips from a local chip shop and requested them to buy him cold medicines on the way.

This shows us that the world we live in today most industries have found ways and developed systems to serve immediate needs of their users but healthcare providers seem to be lagging. …

On the 26th of May, I did a keynote on future of healthcare at the Charité Entrepreneurship Summit 2016 to an audience composed of investors, entrepreneurs and healthcare professionals (Charite Hospital is the leading centre of excellence in Berlin and plays an important role in education and healthcare entrepreneurship in Germany).
In the panel that followed my talk someone raised an important question about data ownership.

whom belongs the data? seems to be a Google question .. @jensredmer #ChariteSummit

— Michael Greth (@mysharepoint) May 26, 2016

Many decades before Elizabeth Holmes was born, Indian freedom fighter Subhash Bose had the rallying cry Give me blood and I will give you freedom”. This may well have been Theranos’ motto as it championed the cause of patients having direct access to blood testing freeing them from the tyranny of healthcare systems that prevent them from doing so. Bose was not using blood to test for markers of disease. He was fighting a war. But that doesn’t stop Holmes from seeing herself as a revolutionary.

Holmes wants people to be able to have their bloods tested for hundreds or…

Vishal Gulati

I back founders who are using data to change healthcare. @VishalGulati_

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